Restricting access to a S3 Form in Smart office only

Is it possible to restrict access to a S3 Form in Smart Office only while allowing users access to the form in Portal? Basically we have some Design Studio mods to a custom form that all  users access. However Smart Office does not apply the customizations and is only available to power users. Is it possible to remove access to the Form from smart office while not impacting the DS access for that form?