Using MFA for Lawson S3 Access

Does anyone use Multi Factor Authentication when users are accessing S3 Portal from the internet/DMZ?

I have not been able to find any useful content on this issue, but I assume there are folks that there are some folks out there somewhere that utilize MFA for S3.

Please advise if you have done so and are willing to share your experience and shed soe insight on the process. (...where you found useful information & documentation on the processpros, cons, any personal insight, etc...)

Thank you in advance for any information you might share.