turning on remoteglt

Any ramifications if I turn on the flag to create the remoteglt file at any point, as opposed to the beginning of a fiscal/calendar/legislative/whatever year? One of our payrolls has never used any type of an automated financial interface, and we'd like to start, sooner rather than later. We don't use Lawson financials here -

As a severely GL Challenged individual, I welcome any suggestions!! Thank you!